| Attribute | Details |
|---|---|
| Active Ingredients | Pioglitazone, Metformin |
| Dosage Forms | 15mg/500mg, 15mg/850mg |
| Therapeutic Use | Type 2 Diabetes |
| Administration Route | Oral |
| Storage Conditions | Room Temperature |
| Learn More About Actoplus Met | |
Pharmacokinetics
Actoplus Met combines pioglitazone and metformin. Pioglitazone undergoes hepatic metabolism. It primarily binds to albumin. Metformin is excreted renally, remaining unchanged in urine. Together, they offer synergistic glycemic control. Pioglitazone shows a half-life of 3 to 7 hours, while metformin’s half-life is about 6.5 hours. Both are absorbed in the gastrointestinal tract. The onset of action occurs within hours, peaking around 2 hours for metformin and 2-4 hours for pioglitazone.
Areas of Use
Actoplus Met targets Type 2 diabetes management. It improves insulin sensitivity and reduces hepatic glucose production. Suitable for adults unable to control blood sugar with diet and exercise alone. Actoplus Met 15mg/500mg is an effective option. It supports long-term glucose stabilization. Prescribers often consider it for patients with obesity-related insulin resistance. It complements lifestyle interventions, aiming to prevent diabetes complications.
Who Can and Cannot Take Actoplus Met
Actoplus Met suits adults with Type 2 diabetes. It’s contraindicated in Type 1 diabetes or diabetic ketoacidosis. Avoid in severe renal impairment. Not recommended for patients with active liver disease. Caution in elderly patients or those with heart failure. Discuss with a healthcare provider before use.
Actoplus Met Storage
Store Actoplus Met at room temperature. Protect from moisture and light. Keep in the original container with the lid tightly closed. Away from children and pets. Avoid bathroom storage to maintain stability. Ensure expiry dates are checked regularly.
Side Effects
Common side effects include gastrointestinal disturbances. Lactic acidosis is a rare but serious risk. Monitor for signs of liver dysfunction. Hypoglycemia risk increases when combined with other antidiabetics. Peripheral edema may occur due to pioglitazone. Report any unusual symptoms promptly.
Actoplus Met for Sale Online
Actoplus Met can be purchased through certified online pharmacies. Ensure the authenticity of the seller. A valid prescription is required. Compare prices for cost-effectiveness. Review customer feedback for reliability. Be cautious of counterfeit products.
| Potential Interactions | Effect |
|---|---|
| Insulin | Increased hypoglycemia risk |
| ACE inhibitors | May enhance glucose-lowering effect |
| Corticosteroids | Potential for hyperglycemia |
- Consult a healthcare professional before starting Actoplus Met.
- Maintain a balanced diet and exercise regimen.
- Monitor blood sugar levels regularly.
